Analysis of Competing Risks Data with Missing Cause of Failure under Additive Hazards Model
نویسندگان
چکیده
Competing risks data arise when study subjects may experience several different types of failure. It is common that the cause of failure is missing due to various reasons. Analysis of competing risks data with missing cause of failure has received considerable attention recently (Goetghebeur and Ryan (1995), Lu and Tsiatis (2001), Gao and Tsiatis (2005), among others). In this article, we study the semiparametric additive hazards model for analysis of competing risk data with missing cause of failure. Different estimating equation approaches using the inverse probability weighted and double robust techniques are proposed for estimating the regression parameters of interest. The resulting estimators have closed forms and their theoretical properties are established for inference. Simultaneous confidence bands of survival curves are constructed using a resampling technique. Simulations and an example show that the proposed approach is appropriate for practical use.
منابع مشابه
Semiparametric inference of competing risks data with additive hazards and missing cause of failure under MCAR or MAR assumptions
متن کامل
Comparison of Random Survival Forests for Competing Risks and Regression Models in Determining Mortality Risk Factors in Breast Cancer Patients in Mahdieh Center, Hamedan, Iran
Introduction: Breast cancer is one of the most common cancers among women worldwide. Patients with cancer may die due to disease progression or other types of events. These different event types are called competing risks. This study aimed to determine the factors affecting the survival of patients with breast cancer using three different approaches: cause-specific hazards regression, subdistri...
متن کاملMissing covariates in competing risks analysis
Studies often follow individuals until they fail from one of a number of competing failure types. One approach to analyzing such competing risks data involves modeling the cause-specific hazards as functions of baseline covariates. A common issue that arises in this context is missing values in covariates. In this setting, we first establish conditions under which complete case analysis (CCA) i...
متن کاملRegression Analysis of Competing Risks Data with General Missing Pattern in Failure Types
In competing risks data, missing failure types (causes) is a very common phenomenon. In a general missing pattern, if a failure type is not observed, one observes a set of possible types containing the true type along with the failure time. Dewanji and Sengupta (2003) considered nonparametric estimation of the cause-specific hazard rates and suggested a Nelson-Aalen type estimator under such ge...
متن کاملParametric Estimation in a Recurrent Competing Risks Model
A resource-efficient approach to making inferences about the distributional properties of the failure times in a competing risks setting is presented. Efficiency is gained by observing recurrences of the compet- ing risks over a random monitoring period. The resulting model is called the recurrent competing risks model (RCRM) and is coupled with two repair strategies whenever the system fails. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2007